March 2023

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The cholinergic anti-inflammatory pathway in chronic kidneydisease—review and vagus nerve stimulation clinical pilot study

Marie Hilderman1 and Annette Bruchfeld1,2 ABSTRAC: TInflammation and autonomic dysfunction are common find-ings in chronic and end-stage kidney disease and contribute to amarkedly increased risk of mortality in this patient population.The cholinergic anti-inflammatory pathway (CAP) is a vagalneuro-immune circuit that upholds the homoeostatic balanceof inflammatory activity in response to cell injury and patho-gens. CAP models have been

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Noninvasive VNS Shown Effective For Symptoms of Vestibular Migraine

Noninvasive vagus nerve stimulation provided rapid relief of vertigo and headache pain caused by acute vestibular migraine (VM), the most common neurologic cause of vertigo, according to a study using retrospective chart review. The study of 18 patients (Neurology 2019;93[18]: e1715-e1719), conducted at a single tertiary referral center between November 2017 and January 2019, found

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