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Background: Severe coronavirus disease 2019 (COVID-19) is characterized, in part, by an excessive inflammatory response. Evidence from animal and human studies suggests that vagus nerve stimulation can lead to reduced levels of various biomarkers of inflammation. We conducted a prospective randomized controlled study (SAVIOR-I) to assess the feasibility, efficacy, and safety of non-invasive vagus nerve […]

Summary: Electrical stimulation of the vagus nerve promotes healing in those with acute inflammation by shifting the balance between inflammatory and anti-inflammatory molecules. Source: Karolinska Institute The nervous system is known to communicate with the immune system and regulate inflammation in the body. Researchers at Karolinska Institutet in Sweden now show how electrical activation of

Emma Paulon,1 Despoina Nastou,1 Francesca Jaboli,1 Juana Marin,2 Eric Liebler,3 Owen Epstein1 1Royal Free London NHS Foundation Trust, London, UK 2NIHR-Wellcome Trust Clinical Research Facility, Queen Elizabeth Hospital, Edgbaston, Birmingham, UK 3electroCore, LLC, Basking Ridge, New Jersey, USA ABSTRACT Background Gastric electric stimulation (GES) is a treatment approach to refractory gastroparesis, possibly acting centrally via afferent vagus nerve stimulation (VNS). Non-invasive VNS (nVNS)

Claire-Marie Rangon and Adam Niezgoda Abstract: The COVID-19 pandemic seems endless with the regular emergence of new variants. Is the SARS-CoV-2 virus particularly evasive to the immune system, or is it merely disrupting communication between the body and the brain, thus pre-empting homeostasis? Retrospective analysis of the COVID-19 and AIDS pandemics, as well as prion disease,